Cryptic crossword clue
Potent anger with one very upset at the outset 6

The most common and most likely answer to this crossword clue is the 6 letter word VIRILE

I've seen this crossword clue in The Daily Telegraph
V
I
R
I
L
E


Buddy explains!

The straight part
We know that "Potent" is the straight/definition part of the clue. The straight part is often a synonym or definition, in this case potent = virile.
The cryptic/wordplay part
In cryptic crossword there's often an wordplay/cryptic part as well.
This part involves a more complex hint, such as an anagram, homophone, hidden word, etc.
Sadly, We don't have an explanation for this specific crossword clue yet.

What does VIRILE mean?

VIRILE adjective
  1. Being manly; having characteristics associated with being male, such as strength; exhibiting masculine traits to an exaggerated degree such as strength, forcefulness or vigor.
  2. (of a male) Possessing high sexual drive and capacity for sexual intercourse.
  3. (grammar) Pertaining to a grammatical gender used in plurals of some Slavic languages, corresponding to the personal masculine animate nouns.

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