Cryptic crossword clue
Powerful shot built up runner 10

The most common and most likely answer to this crossword clue is the 10 letter word PILEDRIVER

P
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E
D
R
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R

Buddy explains!

The straight part
We know that "Powerful shot" is the straight/definition part of the clue. The straight part is often a synonym or definition, in this case powerful shot = piledriver.
The cryptic/wordplay part
In cryptic crossword there's often an wordplay/cryptic part as well.
This part involves a more complex hint, such as an anagram, homophone, hidden word, etc.
Sadly, We don't have an explanation for this specific crossword clue yet.

What does PILEDRIVER mean?

PILEDRIVER noun
  1. A machine for forcing a pile, a long beam, into the ground as part of the construction of a foundation; usually by raising a weight and then dropping it on the beam.
  2. A person who hits or attacks forcefully or powerfully.
PILEDRIVER noun
  1. A move in which the wrestler applies a front waist lock, then drives the opponent's head into the mat by falling to his knees or backside.
  2. A very hard shot.

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