Cryptic crossword clue
Practical instruction limerick writer ignored? 2-8

The most common and most likely answer to this crossword clue is the 11 letter word NO-NONSENSE

I've seen this crossword clue in The Times
N
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Buddy explains!

The straight part
We know that "Practical" is the straight/definition part of the clue. The straight part is often a synonym or definition, in this case practical = no-nonsense.
The cryptic/wordplay part
In cryptic crossword there's often an wordplay/cryptic part as well.
This part involves a more complex hint, such as an anagram, homophone, hidden word, etc.
Sadly, We don't have an explanation for this specific crossword clue yet.

What does NO-NONSENSE mean?

NO-NONSENSE adjective
  1. Practical, not concerning oneself with anything silly or unimportant.

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