Cryptic crossword clue
Practical joke, tho', not beginning with a kiss 4

The most common and most likely answer to this crossword clue is the 4 letter word HOAX

H
O
A
X


Buddy explains!

The straight part
We know that "Practical joke" is the straight/definition part of the clue. The straight part is often a synonym or definition, in this case practical joke = hoax.
The cryptic/wordplay part
In cryptic crossword there's often an wordplay/cryptic part as well.
This part involves a more complex hint, such as an anagram, homophone, hidden word, etc.
Sadly, We don't have an explanation for this specific crossword clue yet.

What does HOAX mean?

HOAX noun
  1. Anything deliberately intended to deceive or trick.
HOAX verb
  1. To deceive (someone) by making them believe something that has been maliciously or mischievously fabricated.

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