Cryptic crossword clue
Prayer leader? I am a medium 4

The most common and most likely answer to this crossword clue is the 4 letter word IMAM

I
M
A
M


Buddy explains!

The straight part
We know that "Prayer leader" is the straight/definition part of the clue. The straight part is often a synonym or definition, in this case prayer leader = imam.
The cryptic/wordplay part
In cryptic crossword there's often an wordplay/cryptic part as well.
This part involves a more complex hint, such as an anagram, homophone, hidden word, etc.
Sadly, We don't have an explanation for this specific crossword clue yet.

What does IMAM mean?

IMAM noun
  1. (usually capitalized) A Shi'ite Muslim leader.
  2. One who leads the salat prayers in a mosque.

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