The most common and most likely answer to this crossword clue is the 5 plus 7 letter word BIBLE THUMPER
I've seen this crossword clue in The Times
B
I
B
L
E
T
H
U
M
P
E
R
Buddy explains!
The straight part
We know that "Preacher" is the straight/definition part of the clue. The straight part is often a synonym or definition, in this case preacher = bible thumper.The cryptic/wordplay part
In cryptic crossword there's often an wordplay/cryptic part as well.This part involves a more complex hint, such as an anagram, homophone, hidden word, etc.
Sadly, We don't have an explanation for this specific crossword clue yet.