Cryptic crossword clue
Prescribe tots no pre-treatment in this medicine 10

The most common and most likely answer to this crossword clue is the 10 letter word OBSTETRICS

O
B
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Buddy explains!

The straight part
We know that "this medicine" is the straight/definition part of the clue. The straight part is often a synonym or definition, in this case this medicine = obstetrics.
The cryptic/wordplay part
In cryptic crossword there's often an wordplay/cryptic part as well.
This part involves a more complex hint, such as an anagram, homophone, hidden word, etc.
Sadly, We don't have an explanation for this specific crossword clue yet.

What does OBSTETRICS mean?

OBSTETRICS noun
  1. The care of women during and after pregnancy

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