The most common and most likely answer to this crossword clue is the 5 letter word BRUNT
B
R
U
N
T
Buddy explains!
The straight part
We know that "Pressure" is the straight/definition part of the clue. The straight part is often a synonym or definition, in this case pressure = brunt.The cryptic/wordplay part
In cryptic crossword there's often an wordplay/cryptic part as well.This part involves a more complex hint, such as an anagram, homophone, hidden word, etc.
Sadly, We don't have an explanation for this specific crossword clue yet.
What does BRUNT mean?
BRUNT noun- The full adverse effects; the chief consequences or negative results of a thing or event.
- The major part of something; the bulk.
- To bear the brunt of; to weather or withstand.