Cryptic crossword clue
Presumed Hypatia has set a toughie, starting earlier 8

The most common and most likely answer to this crossword clue is the 8 letter word PUTATIVE

P
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T
A
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Buddy explains!

The straight part
We know that "Presumed" is the straight/definition part of the clue. The straight part is often a synonym or definition, in this case presumed = putative.
The cryptic/wordplay part
In cryptic crossword there's often an wordplay/cryptic part as well.
This part involves a more complex hint, such as an anagram, homophone, hidden word, etc.
Sadly, We don't have an explanation for this specific crossword clue yet.

What does PUTATIVE mean?

PUTATIVE adjective
  1. Commonly believed or deemed to be the case; accepted by supposition rather than as a result of proof.

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