The most common and most likely answer to this crossword clue is the 6 letter word PRIORS
I've seen this crossword clue in The Daily Telegraph
P
R
I
O
R
S
More clues leading to the result PRIORS
Buddy explains!
The straight part
We know that "religious leaders" is the straight/definition part of the clue. The straight part is often a synonym or definition, in this case religious leaders = priors.The cryptic/wordplay part
In cryptic crossword there's often an wordplay/cryptic part as well.This part involves a more complex hint, such as an anagram, homophone, hidden word, etc.
Sadly, We don't have an explanation for this specific crossword clue yet.
What does PRIORS mean?
PRIORS noun- A high-ranking member of a monastery, usually lower in rank than an abbot.
- A chief magistrate in Italy.
- (law enforcement) A previous arrest or criminal conviction on someone's record.
- In Bayesian inference, a prior probability distribution, one based on information or belief before additional data is collected.