The most common and most likely answer to this crossword clue is the 13 letter word SELF-RELIANCE
I've seen this crossword clue in The Guardian
S
E
L
F
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R
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L
I
A
N
C
E
Buddy explains!
The straight part
We know that "independence" is the straight/definition part of the clue. The straight part is often a synonym or definition, in this case independence = self-reliance.The cryptic/wordplay part
In cryptic crossword there's often an wordplay/cryptic part as well.This part involves a more complex hint, such as an anagram, homophone, hidden word, etc.
Sadly, We don't have an explanation for this specific crossword clue yet.
What does SELF-RELIANCE mean?
SELF-RELIANCE noun- The capacity to rely on one's own capabilities, and to manage one's own affairs; independence.