Cryptic crossword clue
Print worker's firm may initially locate in deprived environment 10

The most common and most likely answer to this crossword clue is the 10 letter word COMPOSITOR

C
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Buddy explains!

The straight part
We know that "Print worker" is the straight/definition part of the clue. The straight part is often a synonym or definition, in this case print worker = compositor.
The cryptic/wordplay part
In cryptic crossword there's often an wordplay/cryptic part as well.
This part involves a more complex hint, such as an anagram, homophone, hidden word, etc.
Sadly, We don't have an explanation for this specific crossword clue yet.

What does COMPOSITOR mean?

COMPOSITOR noun
  1. A person who sets type; a typesetter.
  2. One who, or that which, composes or sets in order.

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