Cryptic crossword clue
Pro has messed up since, on scientific investigation 8

The most common and most likely answer to this crossword clue is the 8 letter word FORENSIC

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Buddy explains!

The straight part
We know that "on scientific investigation" is the straight/definition part of the clue. The straight part is often a synonym or definition, in this case on scientific investigation = forensic.
The cryptic/wordplay part
In cryptic crossword there's often an wordplay/cryptic part as well.
This part involves a more complex hint, such as an anagram, homophone, hidden word, etc.
Sadly, We don't have an explanation for this specific crossword clue yet.

What does FORENSIC mean?

FORENSIC adjective
  1. Relating to the use of science and technology in the investigation and establishment of facts or evidence in a court of law.
  2. Relating to, or appropriate for, courts of law.
  3. Relating to, or used in, debate or argument.

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