Cryptic crossword clue
Problem with gum – is it giving out? 10

The most common and most likely answer to this crossword clue is the 10 letter word GINGIVITIS

I've seen this crossword clue in Financial Times
G
I
N
G
I
V
I
T
I
S

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The cryptic/wordplay part
In cryptic crossword there's often an wordplay/cryptic part as well.
This part involves a more complex hint, such as an anagram, homophone, hidden word, etc.
Sadly, We don't have an explanation for this specific crossword clue yet.

What does GINGIVITIS mean?

GINGIVITIS noun
  1. Inflammation of the gums or gingivae.

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