Cryptic crossword clue
Product of Gilbert, heading off with it 8

The most common and most likely answer to this crossword clue is the 8 letter word LIBRETTI

I've seen this crossword clue in Independent
L
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I


Buddy explains!

The straight part
We know that "Product of Gilbert, heading off with it" is the straight/definition part of the clue. The straight part is often a synonym or definition, in this case product of gilbert, heading off with it = libretti.
The cryptic/wordplay part
In cryptic crossword there's often an wordplay/cryptic part as well.
This part involves a more complex hint, such as an anagram, homophone, hidden word, etc.
Sadly, We don't have an explanation for this specific crossword clue yet.

What does LIBRETTI mean?

LIBRETTI noun
  1. The text of a dramatic musical work, such as an opera.
  2. A book containing such a text.

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