The most common and most likely answer to this crossword clue is the 8 letter word LIFT-OFF
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Buddy explains!

The cryptic/wordplay part
In cryptic crossword there's often an wordplay/cryptic part as well.This part involves a more complex hint, such as an anagram, homophone, hidden word, etc.
Sadly, We don't have an explanation for this specific crossword clue yet.
What does LIFT-OFF mean?
LIFT-OFF noun- The point in the launch of a rocket or an aircraft where it leaves contact with the ground.
- The point at which a person or animal leaves the ground, as for example when jumping.