Cryptic crossword clue
Pub user twisted bottom of leg, getting nasty strain 8

The most common and most likely answer to this crossword clue is the 8 letter word SUPERBUG

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The cryptic/wordplay part
In cryptic crossword there's often an wordplay/cryptic part as well.
This part involves a more complex hint, such as an anagram, homophone, hidden word, etc.
Sadly, We don't have an explanation for this specific crossword clue yet.

What does SUPERBUG mean?

SUPERBUG noun
  1. A strain of bacteria that is resistant to many antibiotics.
  2. Any pathogen resistant to many, even all, of the biocides or other agents used to treat similar pathogens.
  3. An invasive insect, Bemisia tabaci, that is a major pest of vegetable crops, both directly and as a virus vector.

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