The most common and most likely answer to this crossword clue is the 8 letter word PRATTLER
P
R
A
T
T
L
E
R
More clues leading to the result PRATTLER
Buddy explains!
The straight part
We know that "one can go on and on" is the straight/definition part of the clue. The straight part is often a synonym or definition, in this case one can go on and on = prattler.The cryptic/wordplay part
In cryptic crossword there's often an wordplay/cryptic part as well.This part involves a more complex hint, such as an anagram, homophone, hidden word, etc.
Sadly, We don't have an explanation for this specific crossword clue yet.