Cryptic crossword clue
Puffed up? One man’s the opposite of that inside 8

The most common and most likely answer to this crossword clue is the 8 letter word INFLATED

I've seen this crossword clue in The Daily Telegraph
I
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Buddy explains!

The straight part
We know that "Puffed up" is the straight/definition part of the clue. The straight part is often a synonym or definition, in this case puffed up = inflated.
The cryptic/wordplay part
In cryptic crossword there's often an wordplay/cryptic part as well.
This part involves a more complex hint, such as an anagram, homophone, hidden word, etc.
Sadly, We don't have an explanation for this specific crossword clue yet.

What does INFLATED mean?

INFLATED verb
  1. To enlarge an object by pushing air (or a gas) into it; to raise or expand abnormally
  2. To enlarge by filling with air (or a gas).
  3. To swell; to puff up.
  4. To decompress (data) that was previously deflated.
INFLATED adjective
  1. Filled with air or fluid
  2. Expanded; in a state of inflation, of abnormally increased size, amount, etc.
  3. : In a state of higher cost.
  4. Pompous; arrogant (of a person or ego)
  5. Containing excessive, meaningless words, particularly for show
  6. Higher that the true figure

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