Cryptic crossword clue
Pull on weed relentlessly shackles donkey 5-5

The most common and most likely answer to this crossword clue is the 11 letter word CHAIN-SMOKE

I've seen this crossword clue in Independent
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Buddy explains!

The straight part
We know that "Pull on weed relentlessly" is the straight/definition part of the clue. The straight part is often a synonym or definition, in this case pull on weed relentlessly = chain-smoke.
The cryptic/wordplay part
In cryptic crossword there's often an wordplay/cryptic part as well.
This part involves a more complex hint, such as an anagram, homophone, hidden word, etc.
Sadly, We don't have an explanation for this specific crossword clue yet.

What does CHAIN-SMOKE mean?

CHAIN-SMOKE verb
  1. To smoke cigarettes by continuously lighting one from the glowing end of the previous one.
  2. To smoke tobacco cigarettes frequently.
  3. To smoke by continuously lighting one from another.

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