Cryptic crossword clue
Purgative requiring vacant loo in plane 7

The most common and most likely answer to this crossword clue is the 7 letter word CALOMEL

I've seen this crossword clue in Financial Times
C
A
L
O
M
E
L

Buddy explains!

The straight part
We know that "Purgative" is the straight/definition part of the clue. The straight part is often a synonym or definition, in this case purgative = calomel.
The cryptic/wordplay part
In cryptic crossword there's often an wordplay/cryptic part as well.
This part involves a more complex hint, such as an anagram, homophone, hidden word, etc.
Sadly, We don't have an explanation for this specific crossword clue yet.

What does CALOMEL mean?

CALOMEL noun
  1. Mercurous chloride Hg2Cl2, formerly used as a laxative and disinfectant and to treat syphilis

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