Cryptic crossword clue
Pushy parent ultimately spreading disease 6

The most common and most likely answer to this crossword clue is the 6 letter word TYPHUS

I've seen this crossword clue in The Guardian
T
Y
P
H
U
S

Buddy explains!

The straight part
We know that "disease" is the straight/definition part of the clue. The straight part is often a synonym or definition, in this case disease = typhus.
The cryptic/wordplay part
In cryptic crossword there's often an wordplay/cryptic part as well.
This part involves a more complex hint, such as an anagram, homophone, hidden word, etc.
Sadly, We don't have an explanation for this specific crossword clue yet.

What does TYPHUS mean?

TYPHUS noun
  1. One of several similar diseases, characterised by high recurrent fever, caused by Rickettsia bacteria. Not to be confused with typhoid fever.

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