The most common and most likely answer to this crossword clue is the 6 letter word HUMOUR
I've seen this crossword clue in The Guardian
H
U
M
O
U
R
More clues leading to the result HUMOUR
- Sense of wit I’m not sure is found in time
- Bodily fluid gags?
- Put up with unpleasant smell visiting old university rector
- Comedy occasion contains unlimited smut, on reflection
- Smell attached to old biblical city? That’s funny!
- Time to overcome hesitation with wit
- … comedy blood?
- Pretend to agree with expression of doubt, filling time
Buddy explains!

The cryptic/wordplay part
In cryptic crossword there's often an wordplay/cryptic part as well.This part involves a more complex hint, such as an anagram, homophone, hidden word, etc.
Sadly, We don't have an explanation for this specific crossword clue yet.
What does HUMOUR mean?
HUMOUR noun- The quality of being amusing, comical, funny.
- A mood, especially a bad mood; a temporary state of mind or disposition brought upon by an event; an abrupt illogical inclination or whim.
- Any of the fluids in an animal body, especially the four "cardinal humours" of blood, yellow bile, black bile and phlegm that were believed to control the health and mood of the human body.
- Either of the two regions of liquid within the eyeball, the aqueous humour and vitreous humour.
- Moist vapour, moisture.
- To pacify by indulging.