The most common and most likely answer to this crossword clue is the 4 plus 2 plus 3 letter word LOST AT SEA
L
O
S
T
A
T
S
E
A
More clues leading to the result LOST AT SEA
Buddy explains!

The straight part
We know that "Puzzled" is the straight/definition part of the clue. The straight part is often a synonym or definition, in this case puzzled = lost at sea.The cryptic/wordplay part
In cryptic crossword there's often an wordplay/cryptic part as well.This part involves a more complex hint, such as an anagram, homophone, hidden word, etc.
Sadly, We don't have an explanation for this specific crossword clue yet.