Cryptic crossword clue
Quarantine island, run down, containing nothing 7

The most common and most likely answer to this crossword clue is the 7 letter word ISOLATE

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The cryptic/wordplay part
In cryptic crossword there's often an wordplay/cryptic part as well.
This part involves a more complex hint, such as an anagram, homophone, hidden word, etc.
Sadly, We don't have an explanation for this specific crossword clue yet.

What does ISOLATE mean?

ISOLATE noun
  1. Something that has been isolated.
ISOLATE verb
  1. To set apart or cut off from others.
  2. To place in quarantine or isolation.
  3. To separate a substance in pure form from a mixture.
  4. To insulate, or make free of external influence.
  5. To separate a pure strain of bacteria etc. from a mixed culture.
  6. To insulate an electrical component from a source of electricity.

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