Cryptic crossword clue
Quarter of Rome, among 100 there – it features on many of its signs 6

The most common and most likely answer to this crossword clue is the 6 letter word CENTRO

C
E
N
T
R
O

Buddy explains!

The straight part
We know that "it features on many of its signs" is the straight/definition part of the clue. The straight part is often a synonym or definition, in this case it features on many of its signs = centro.
The cryptic/wordplay part
In cryptic crossword there's often an wordplay/cryptic part as well.
This part involves a more complex hint, such as an anagram, homophone, hidden word, etc.
Sadly, We don't have an explanation for this specific crossword clue yet.


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