The most common and most likely answer to this crossword clue is the 9 letter word ALEXANDRA
I've seen this crossword clue in The Times
A
L
E
X
A
N
D
R
A
More clues leading to the result ALEXANDRA
- Queen cross with regiment holding up drink
- Porter cross with artist portraying Queen
- Russian empress one departing Mediterranean port
- Old queen’s maybe bitter times with artist
- I left Egyptian city for a girl
- Jump back in and begin ruining a palace
- English princess, one leaving port on the Nile Delta
- Palace international vanished from capital once
Buddy explains!

The straight part
We know that "Queen" is the straight/definition part of the clue. The straight part is often a synonym or definition, in this case queen = alexandra.The cryptic/wordplay part
In cryptic crossword there's often an wordplay/cryptic part as well.This part involves a more complex hint, such as an anagram, homophone, hidden word, etc.
Sadly, We don't have an explanation for this specific crossword clue yet.