Cryptic crossword clue
Queen Victoria’s beginning to interrupt all her children, quelling excitement? 7

The most common and most likely answer to this crossword clue is the 7 letter word NERVINE

I've seen this crossword clue in The Guardian
N
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Buddy explains!

The straight part
We know that "quelling excitement?" is the straight/definition part of the clue. The straight part is often a synonym or definition, in this case quelling excitement? = nervine.
The cryptic/wordplay part
In cryptic crossword there's often an wordplay/cryptic part as well.
This part involves a more complex hint, such as an anagram, homophone, hidden word, etc.
Sadly, We don't have an explanation for this specific crossword clue yet.

What does NERVINE mean?

NERVINE noun
  1. A drug or substance that acts upon the nerves.
NERVINE adjective
  1. Having the quality of acting upon or affecting the nerves; quieting nervous excitement.

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