Cryptic crossword clue
Queen’s picked up laxative for driver 5

The most common and most likely answer to this crossword clue is the 5 letter word SENNA

I've seen this crossword clue in Independent
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Buddy explains!

The straight part
We know that "driver" is the straight/definition part of the clue. The straight part is often a synonym or definition, in this case driver = senna.
The cryptic/wordplay part
In cryptic crossword there's often an wordplay/cryptic part as well.
This part involves a more complex hint, such as an anagram, homophone, hidden word, etc.
Sadly, We don't have an explanation for this specific crossword clue yet.

What does SENNA mean?

SENNA noun
  1. Any of several plants of the tribe Cassieae, especially those of the genera Cassia and Senna, whose leaves and pods are used as a purgative and laxative.
  2. The dried leaves or pods of these plants (especially of Senna alexandrina, syn. Cassia angustifolia or Cassia acutifolia), used medicinally.
  3. Senna glycoside, a laxative.

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