The most common and most likely answer to this crossword clue is the 4 letter word PURE
P
U
R
E
More clues leading to the result PURE
- Utter excitedly about joining Royal Engineers
- Climbing up sides of ridge, sheer
- Sheer power shown by river
- 100% leather upholstery covers from bottom up
- How to make smoothies virtually free of contaminants
- Most of mashed potato is white
- Natural and mostly thick liquid
- Unmixed, last of ginger beer stirred into dessert
- Quiet river or mere
Buddy explains!

The straight part
We know that "mere" is the straight/definition part of the clue. The straight part is often a synonym or definition, in this case mere = pure.The cryptic/wordplay part
In cryptic crossword there's often an wordplay/cryptic part as well.This part involves a more complex hint, such as an anagram, homophone, hidden word, etc.
Sadly, We don't have an explanation for this specific crossword clue yet.
What does PURE mean?
PURE noun- One who, or that which, is pure.
- To hit (the ball) completely cleanly and accurately
- To cleanse; to refine.
- Free of flaws or imperfections; unsullied.
- Free of foreign material or pollutants.
- Free of immoral behavior or qualities; clean.
- Mere; that and that only.
- (of a branch of science) Done for its own sake instead of serving another branch of science.
- Of a single, simple sound or tone; said of some vowels and the unaspirated consonants.
- (of sound) Without harmonics or overtones; not harsh or discordant.
- To a great extent or degree; extremely; exceedingly.
- Dung (of dogs, fowls, etc) used in tanning, after applying lime, to soften skins.
- An archetype of eternal youth; (loosely), a man who remains emotionally childlike.