The most common and most likely answer to this crossword clue is the 4 letter word SOHO
I've seen this crossword clue in The Times
S
O
H
O
More clues leading to the result SOHO
- Quietly leaves store, touring old part of London
- Endless things for tiller to do in London area
- London area of note with nothing
- Very hot temperature leaves part of London noticeably steamy
- Very hard getting round London district
- London section starts to spy on Home Office
- Naked co-host returning to red-light district
- . Openings in Somerset House and in W1
- Part of West End not quite as fashionable
- Area of London is posh now, having evicted odd characters
Buddy explains!
The straight part
We know that "part of London" is the straight/definition part of the clue. The straight part is often a synonym or definition, in this case part of london = soho.The cryptic/wordplay part
In cryptic crossword there's often an wordplay/cryptic part as well.This part involves a more complex hint, such as an anagram, homophone, hidden word, etc.
Sadly, We don't have an explanation for this specific crossword clue yet.
What does SOHO mean?
SOHO interjection- Ho; halloo; a word used in calling from a distant place.