The most common and most likely answer to this crossword clue is the 6 letter word DEPART
I've seen this crossword clue in The Daily Telegraph
D
E
P
A
R
T
More clues leading to the result DEPART
- Hurry to collect record - go!
- Leave extremely disreputable sector
- Wander off track with record-holder Bolt?
- Go when penultimate lap ends in race
- Leave from French region
- Put old record in missile and take off
- Set off in race holding record
- Dame, gutted with supporting role, is to leave
- Go quiet during precious time
- Start out with extremely diverse role
Buddy explains!

The straight part
We know that "Qui" is the straight/definition part of the clue. The straight part is often a synonym or definition, in this case qui = depart.The cryptic/wordplay part
In cryptic crossword there's often an wordplay/cryptic part as well.This part involves a more complex hint, such as an anagram, homophone, hidden word, etc.
Sadly, We don't have an explanation for this specific crossword clue yet.
What does DEPART mean?
DEPART noun- Division; separation, as of compound substances.
- A going away; departure.
- To leave.
- To set out on a journey.
- To die.
- To disappear, vanish; to cease to exist.
- To deviate (from), be different (from), fail to conform.
- To go away from; to leave.
- To divide up; to distribute, share.
- To separate, part.