Cryptic crossword clue
Quite a selection including prickly plant 6

The most common and most likely answer to this crossword clue is the 6 letter word TEASEL

I've seen this crossword clue in The Times
T
E
A
S
E
L


Buddy explains!

The straight part
We know that "prickly plant" is the straight/definition part of the clue. The straight part is often a synonym or definition, in this case prickly plant = teasel.
The cryptic/wordplay part
In cryptic crossword there's often an wordplay/cryptic part as well.
This part involves a more complex hint, such as an anagram, homophone, hidden word, etc.
Sadly, We don't have an explanation for this specific crossword clue yet.

What does TEASEL mean?

TEASEL noun
  1. Any of several plants of the genus Dipsacus.
  2. The dried flower head of the fuller's teasel, Dipsacus fullonum, used for teasing or carding cloth.
  3. Any contrivance intended as a substitute for teasels in dressing cloth.
TEASEL verb
  1. To raise the nap on cloth; to tease; to card.

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