The most common and most likely answer to this crossword clue is the 6 letter word TREBLE
T
R
E
B
L
E
More clues leading to the result TREBLE
- Singer’s baggage initially left in plane, perhaps
- As singer, be very apprehensive to miss mass
- High belter!
- Quiver, losing heart in large measure
- Choirboy to quiver missing mass
- Singer with note left in service, say
- Show fear, losing heart: stiff drink needed
- Multiple bet of boy soprano
- Make three times as much as Bert backing the French
- Apple for one, hugging band’s leader, lost voice
Buddy explains!

The straight part
We know that "large measure" is the straight/definition part of the clue. The straight part is often a synonym or definition, in this case large measure = treble.The cryptic/wordplay part
In cryptic crossword there's often an wordplay/cryptic part as well.This part involves a more complex hint, such as an anagram, homophone, hidden word, etc.
Sadly, We don't have an explanation for this specific crossword clue yet.
What does TREBLE mean?
TREBLE noun- The highest singing voice (especially as for a boy) or part in musical composition.
- A person or instrument having a treble voice or pitch; a boy soprano.
- The highest tuned in a ring of bells.
- Any high-pitched or shrill voice or sound.
- A threefold quantity or number; something having three parts or having been tripled.
- A drink with three portions of alcohol.
- Any of the narrow areas enclosed by the two central circles on a dartboard, worth three times the usual value of the segment.
- Three goals, victories, awards etc. in a given match or season.
- To multiply by three; to make into three parts, layers, or thrice the amount.
- To become multiplied by three or increased threefold.
- To make a shrill or high-pitched noise.
- To utter in a treble key; to whine.
- Pertaining to the highest singing voice or part in harmonized music; soprano.
- High in pitch; shrill.
- Threefold, triple.
- Trebly; triply.