The most common and most likely answer to this crossword clue is the 5 letter word MILAN
I've seen this crossword clue in Financial Times
M
I
L
A
N
More clues leading to the result MILAN
- City gent bringing in one pound
- Italian city gent steals Sicilian's heart
- Staff outside the Italian financial centre
- Italian city somewhat international I mean, on reflection
- US city in time becoming a city in Europe
- Foreign city that’s lost nothing in translation
- Children’s author not entirely captivating a European city
- Race to consume one litre in Italian location
- Piece about one large city
- Note left the heart of Scandi fashion capital
Buddy explains!

The straight part
We know that "Italian location" is the straight/definition part of the clue. The straight part is often a synonym or definition, in this case italian location = milan.The cryptic/wordplay part
In cryptic crossword there's often an wordplay/cryptic part as well.This part involves a more complex hint, such as an anagram, homophone, hidden word, etc.
Sadly, We don't have an explanation for this specific crossword clue yet.