The most common and most likely answer to this crossword clue is the 4 letter word ROTI
R
O
T
I
Buddy explains!
The straight part
We know that "in /course" is the straight/definition part of the clue. The straight part is often a synonym or definition, in this case in /course = roti.The cryptic/wordplay part
In cryptic crossword there's often an wordplay/cryptic part as well.This part involves a more complex hint, such as an anagram, homophone, hidden word, etc.
Sadly, We don't have an explanation for this specific crossword clue yet.
What does ROTI mean?
ROTI noun- A kind of unleavened flatbread commonly consumed in South Asia and the Caribbean.