Cryptic crossword clue
Rather sour tonic tends to go off 10

The most common and most likely answer to this crossword clue is the 10 letter word DISCONTENT

D
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Buddy explains!

The straight part
We know that "Rather sour" is the straight/definition part of the clue. The straight part is often a synonym or definition, in this case rather sour = discontent.
The cryptic/wordplay part
In cryptic crossword there's often an wordplay/cryptic part as well.
This part involves a more complex hint, such as an anagram, homophone, hidden word, etc.
Sadly, We don't have an explanation for this specific crossword clue yet.

What does DISCONTENT mean?

DISCONTENT noun
  1. Dissatisfaction.
  2. A longing for better times or circumstances.
  3. A discontented person; a malcontent.
DISCONTENT verb
  1. To deprive of contentment; to make uneasy; to dissatisfy.
DISCONTENT adjective
  1. Not content; discontented; dissatisfied.

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