Cryptic crossword clue
Rats in item of clothing 8

The most common and most likely answer to this crossword clue is the 8 letter word KNICKERS

I've seen this crossword clue in Financial Times
K
N
I
C
K
E
R
S


Buddy explains!

The straight part
We know that "Rats/item of clothing" is the straight/definition part of the clue. The straight part is often a synonym or definition, in this case rats/item of clothing = knickers.
The cryptic/wordplay part
In cryptic crossword there's often an wordplay/cryptic part as well.
This part involves a more complex hint, such as an anagram, homophone, hidden word, etc.
Sadly, We don't have an explanation for this specific crossword clue yet.

What does KNICKERS mean?

KNICKERS noun
  1. Knickerbockers.
  2. Women's underpants.
KNICKERS interjection
  1. A mild exclamation of annoyance.

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