Cryptic crossword clue
Rats scurried round in drainage system for skyscraper 5,5

The most common and most likely answer to this crossword clue is the 5 plus 5 letter word SEARS TOWER

S
E
A
R
S
T
O
W
E
R

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The cryptic/wordplay part
In cryptic crossword there's often an wordplay/cryptic part as well.
This part involves a more complex hint, such as an anagram, homophone, hidden word, etc.
Sadly, We don't have an explanation for this specific crossword clue yet.

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