Cryptic crossword clue
Reach hotel passing through South’s traditionally impoverished areas 7

The most common and most likely answer to this crossword clue is the 7 letter word GHETTOS

I've seen this crossword clue in The Guardian
G
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Buddy explains!

The straight part
We know that "traditionally impoverished areas" is the straight/definition part of the clue. The straight part is often a synonym or definition, in this case traditionally impoverished areas = ghettos.
The cryptic/wordplay part
In cryptic crossword there's often an wordplay/cryptic part as well.
This part involves a more complex hint, such as an anagram, homophone, hidden word, etc.
Sadly, We don't have an explanation for this specific crossword clue yet.

What does GHETTOS mean?

GHETTOS noun
  1. An (often walled) area of a city in which Jews are concentrated by force and law. (Used particularly of areas in medieval Italy and in Nazi-controlled Europe.)
  2. An (often impoverished) area of a city inhabited predominantly by members of a specific nationality, ethnicity or race.
  3. An area in which people who are distinguished by sharing something other than ethnicity concentrate or are concentrated.
  4. (sometimes derogatory) An isolated, self-contained, segregated subsection, area or field of interest; often of minority or specialist interest.

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