Cryptic crossword clue
React, bet male just skips topic of discussion 7,6

The most common and most likely answer to this crossword clue is the 7 plus 6 letter word SUBJECT MATTER

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Buddy explains!

The straight part
We know that "topic of discussion" is the straight/definition part of the clue. The straight part is often a synonym or definition, in this case topic of discussion = subject matter.
The cryptic/wordplay part
In cryptic crossword there's often an wordplay/cryptic part as well.
This part involves a more complex hint, such as an anagram, homophone, hidden word, etc.
Sadly, We don't have an explanation for this specific crossword clue yet.

What does SUBJECT MATTER mean?

SUBJECT MATTER noun
  1. The matter or thought presented for consideration in some statement or discussion; that which is made the object of thought or study.

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