Cryptic crossword clue
Reader's issue with English agreed by school 9

The most common and most likely answer to this crossword clue is the 9 letter word EYESTRAIN

I've seen this crossword clue in The Times
E
Y
E
S
T
R
A
I
N


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The straight part
We know that "Reader's issue" is the straight/definition part of the clue. The straight part is often a synonym or definition, in this case reader's issue = eyestrain.
The cryptic/wordplay part
In cryptic crossword there's often an wordplay/cryptic part as well.
This part involves a more complex hint, such as an anagram, homophone, hidden word, etc.
Sadly, We don't have an explanation for this specific crossword clue yet.

What does EYESTRAIN mean?

EYESTRAIN noun
  1. Tiredness or pain in the eyes, sometimes accompanied by headache, caused by excessive or improper use of the eyes, or by uncorrected defects of vision

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