Cryptic crossword clue
Reading up list topped by instrument one may break in? 8

The most common and most likely answer to this crossword clue is the 8 letter word VIOLATOR

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Buddy explains!

The straight part
We know that "one may break in?" is the straight/definition part of the clue. The straight part is often a synonym or definition, in this case one may break in? = violator.
The cryptic/wordplay part
In cryptic crossword there's often an wordplay/cryptic part as well.
This part involves a more complex hint, such as an anagram, homophone, hidden word, etc.
Sadly, We don't have an explanation for this specific crossword clue yet.

What does VIOLATOR mean?

VIOLATOR noun
  1. One who violates (a rule, a boundary, another person's body, etc.); offender
  2. In the publishing and packaging industries, a visual element that intentionally "violates" the underlying design, such as a starburst, color bar or "splat" on a product package or magazine cover intended to attract special attention.

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