The most common and most likely answer to this crossword clue is the 6 letter word HONEST
I've seen this crossword clue in The Guardian
H
O
N
E
S
T
More clues leading to the result HONEST
- Decent hotel on East Street
- Genuine in path one’s taken
- Polish street behind this square
- Frank does cutting-edge work ahead of time
- Just a house — use as place of retreat
- Trusty hen’s first over place to hatch eggs
- Frank does cutting-edge work over time
- Real hot Rolling Stone!
- On the ground, holding small upright
- Reputable home for prostitute?
Buddy explains!

The straight part
We know that "Real" is the straight/definition part of the clue. The straight part is often a synonym or definition, in this case real = honest.The cryptic/wordplay part
In cryptic crossword there's often an wordplay/cryptic part as well.This part involves a more complex hint, such as an anagram, homophone, hidden word, etc.
Sadly, We don't have an explanation for this specific crossword clue yet.
What does HONEST mean?
HONEST verb- To adorn or grace; to honour; to make becoming, appropriate, or honourable.
- (of a person or institution) Scrupulous with regard to telling the truth; not given to swindling, lying, or fraud; upright.
- (of a statement) True, especially as far as is known by the person making the statement; fair; unbiased.
- In good faith; without malice.
- (of a measurement device) Accurate.
- Authentic; full.
- Earned or acquired in a fair manner.
- Open; frank.
- Decent; honourable; suitable; becoming.
- Chaste; faithful; virtuous.
- Honestly; really.