Cryptic crossword clue
Real upset about politician is more considerable 6

The most common and most likely answer to this crossword clue is the 6 letter word AMPLER

I've seen this crossword clue in The Daily Telegraph
A
M
P
L
E
R

Buddy explains!

The straight part
We know that "more considerable" is the straight/definition part of the clue. The straight part is often a synonym or definition, in this case more considerable = ampler.
The cryptic/wordplay part
In cryptic crossword there's often an wordplay/cryptic part as well.
This part involves a more complex hint, such as an anagram, homophone, hidden word, etc.
Sadly, We don't have an explanation for this specific crossword clue yet.

What does AMPLER mean?

AMPLER adjective
  1. Large; great in size, extent, capacity, or bulk; for example spacious, roomy or widely extended.
  2. Fully sufficient; abundant; plenty
  3. Not contracted or brief; not concise; extended; diffusive

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