Cryptic crossword clue
Reflexive pronoun is left out 6

The most common and most likely answer to this crossword clue is the 6 letter word ITSELF

I
T
S
E
L
F


Buddy explains!

The straight part
We know that "Reflexive pronoun" is the straight/definition part of the clue. The straight part is often a synonym or definition, in this case reflexive pronoun = itself.
The cryptic/wordplay part
In cryptic crossword there's often an wordplay/cryptic part as well.
This part involves a more complex hint, such as an anagram, homophone, hidden word, etc.
Sadly, We don't have an explanation for this specific crossword clue yet.

What does ITSELF mean?

ITSELF pronoun
  1. (reflexive pronoun) it; A thing as the object of a verb or preposition that also appears as the subject
  2. It; used to intensify the subject, especially to emphasize that it is the only participant in the predicate
  3. It; used to refer back to an earlier subject

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