Cryptic crossword clue
Refulgent, bursting with energy and so more tolerable to some? 6-4

The most common and most likely answer to this crossword clue is the 11 letter word GLUTEN-FREE

I've seen this crossword clue in The Guardian
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Buddy explains!

The straight part
We know that "more tolerable to some?/more tolerable to some?" is the straight/definition part of the clue. The straight part is often a synonym or definition, in this case more tolerable to some?/more tolerable to some? = gluten-free.
The cryptic/wordplay part
In cryptic crossword there's often an wordplay/cryptic part as well.
This part involves a more complex hint, such as an anagram, homophone, hidden word, etc.
Sadly, We don't have an explanation for this specific crossword clue yet.

What does GLUTEN-FREE mean?

GLUTEN-FREE adjective
  1. (of food) Containing no gluten.
  2. (of a person) not eating gluten

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