The most common and most likely answer to this crossword clue is the 6 letter word EQUATE
I've seen this crossword clue in The Daily Telegraph
E
Q
U
A
T
E
More clues leading to the result EQUATE
- Essex opener run out twice in fourth match
- Square hedge, with one very ordinary college out of sight within
- Two Europeans having couple of pints inside run out to see match
- Quite a strange one having fled European match
- Make it the same as in Parisian summer
- Regard alike English queen and retired foreign character
- Men leave for Spain in a line for match
Buddy explains!

The straight part
We know that "Regard alike" is the straight/definition part of the clue. The straight part is often a synonym or definition, in this case regard alike = equate.The cryptic/wordplay part
In cryptic crossword there's often an wordplay/cryptic part as well.This part involves a more complex hint, such as an anagram, homophone, hidden word, etc.
Sadly, We don't have an explanation for this specific crossword clue yet.
What does EQUATE mean?
EQUATE noun- A statement in assembly language that defines a symbol having a particular value.
- To consider equal or equivalent.
- To set as equal.