The most common and most likely answer to this crossword clue is the 5 letter word AREAS
I've seen this crossword clue in The Times
A
R
E
A
S
More clues leading to the result AREAS
- Regions in South Africa with time turned around
- Not covered, ignored at the outset, like the regions
- The regions are as follows
- Places fair bet & pays, regardless of the odds
- Regions in Far East
- Parts of ground in sporting venues not given a name?
- Greek warmonger captures west end of Athenian neighborhoods
- Article in Olympian fields
Buddy explains!

The straight part
We know that "Regions" is the straight/definition part of the clue. The straight part is often a synonym or definition, in this case regions = areas.The cryptic/wordplay part
In cryptic crossword there's often an wordplay/cryptic part as well.This part involves a more complex hint, such as an anagram, homophone, hidden word, etc.
Sadly, We don't have an explanation for this specific crossword clue yet.
What does AREAS mean?
AREAS noun- A measure of the extent of a surface; it is measured in square units.
- A particular geographic region.
- Any particular extent of surface, especially an empty or unused extent.
- The extent, scope, or range of an object or concept.
- An open space, below ground level, between the front of a house and the pavement.
- Penalty box; penalty area.
- Genitals.