Cryptic crossword clue
Regular in the above series put up with remark about fist thrown in anger 10

The most common and most likely answer to this crossword clue is the 10 letter word DISSATISFY

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The cryptic/wordplay part
In cryptic crossword there's often an wordplay/cryptic part as well.
This part involves a more complex hint, such as an anagram, homophone, hidden word, etc.
Sadly, We don't have an explanation for this specific crossword clue yet.

What does DISSATISFY mean?

DISSATISFY verb
  1. To fail to satisfy; to displease.

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